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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF213 All Species: 17.58
Human Site: T266 Identified Species: 64.44
UniProt: Q63HN8 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q63HN8 NP_065965.3 3280 373981 T266 Q E G S V E G T P E E C L Q H
Chimpanzee Pan troglodytes XP_511726 4149 473678 T1172 Q E G S V E G T P E E C L Q H
Rhesus Macaque Macaca mulatta XP_001110315 4229 480306 T1288 Q E G S V E G T P E E C L Q H
Dog Lupus familis XP_540474 3388 386230 T381 Q E G F V E G T P E E C L Q Y
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus XP_001081768 5230 593496 S2244 E K D S V E G S P E E C L Q H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420083 4031 460684 H359 D F D E I L H H L L T W P D V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921030 4291 493201 V1319 D E F L Y Q G V E G S H V E C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.9 66.2 70 N.A. N.A. 46.2 N.A. N.A. 22.9 N.A. 41.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 76.3 70.2 80.7 N.A. N.A. 52.9 N.A. N.A. 39.2 N.A. 55.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. N.A. 73.3 N.A. N.A. 0 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. N.A. 93.3 N.A. N.A. 6.6 N.A. 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 72 0 0 15 % C
% Asp: 29 0 29 0 0 0 0 0 0 0 0 0 0 15 0 % D
% Glu: 15 72 0 15 0 72 0 0 15 72 72 0 0 15 0 % E
% Phe: 0 15 15 15 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 58 0 0 0 86 0 0 15 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 15 15 0 0 0 15 0 0 58 % H
% Ile: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 15 0 15 0 0 15 15 0 0 72 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 72 0 0 0 15 0 0 % P
% Gln: 58 0 0 0 0 15 0 0 0 0 0 0 0 72 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 58 0 0 0 15 0 0 15 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 58 0 0 15 0 0 0 0 % T
% Val: 0 0 0 0 72 0 0 15 0 0 0 0 15 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 % W
% Tyr: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _